The Connecticut College Arboretum is located in southeastern Connecticut, about 5 miles inland from Long Island Sound.  It is located at approximately 830 Williams Street. Follow the directions to Connecticut College, 270 Mohegan Avenue, New London, CT.

The main entrance to the Native Plant Collection is directly across the street from the Williams Street entrance to Connecticut College at Harkness Chapel. Look for the double wrought iron gates with large golden leaves. When visiting the Native Plant Collection, cars may park along Williams Street if space is available. Alternate parking is at 33 Gallows Lane or in the South Parking Lot on the main campus (to park in the South Parking Lot, visitors must obtain a parking permit from the guard house at the main entrance of the College). Tour buses may let passengers out at the main gate on Williams Street, but then must park in the south end of the South Parking Lot on the Connecticut College campus.

The Caroline Black Garden is located across the street from the Connecticut College main entrance.  It is just off Route 32 at 4 Winchester Road; best accessed by taking the road to the College Athletic Center and an immediate right onto Winchester Road. Take a right at the first driveway, which leads to Vinal Cottage. When visiting the Caroline Black Garden, cars can usually fit in the parking lot behind Vinal Cottage.  Buses may let passengers out at the entrance to the parking lot, and then must park at the south end of the South Parking lot on the main campus.

The Arboretum Office is located at 33 Gallows Lane, New London CT 06320 where there is additional parking.

The oak and hemlock forested Bolleswood Natural Area is located west of the Arboretum Pond; the Goodwin Natural Area is north of Gallows Lane; and the rocky, wooded, 40-acre Mamacoke Island in the Thames River is attached to the mainland by a small tidal salt marsh.